Discovery and Basic Research

(T0930-04-22) A Complete Automation Solution Using an Acoustic Ejection Mass Spectrometry System for Rapid Sample Analysis

(M0930-04-23) Beneficial Effects of Trehalose on Mesenchymal Stem Cell-Derived Exosomes

(T0930-04-23) Impact of a Novel Thin Film Platform on the Uptake and Permeability of Virus-Based Vaccines in an In Vitro Model of the Human Oral Mucosa

(W0930-04-23) In Vitro Synergism of Depolymerase-Antibiotic Combination against Multidrug-Resistant Acinetobacter baumannii

(M0930-04-24) Design and Synthesis of Conformationally Modulated Rutinose Saccharides and Their Conformational Analysis by NMR

(T0930-04-24) Urea-Based Compound UR-1-1-13 Affects the Mitochondrial Health of Triple-Negative Breast Cancer Cells

(M0930-04-25) A Compatibility Test of Two-Piece Hard Capsules and Liquid/Semi-solid Excipients - Part 2

(T0930-04-25) ISMICAP: A Model for Delving into Blood-Brain Barrier Mysteries

(W0930-04-25) Physiologically Based Pharmacokinetic (PBPK) Oral Absorption Model to Predict Mucosal Permeability of Oral Cavity Drug Products

(T0930-04-26) A New Class of Lipids Conjugated to Poly(ethylene glycol) Structural Isomers: An Efficient Approach to Evade Immune Recognition of Lipid Nanoparticles

(W0930-04-26) A Novel Poly(N-isopropylacrylamide)-based Thermoresponsive Bioink for DLP Bioprinting

(M0930-04-26) Sodium Butyrate Decreases VCAM-1 Expression by Inhibiting Stat3/GATA6 Signaling Pathway in Alzheimer’s disease

(T0930-04-27) DNA Hydroxymethylation and TET Enzymes Changes Induced by the Curcumin Analog Dimethoxycurcumin

(M0930-04-27) High-Resolution Sequencing Comparison of the DNA Methylome and Hydroxymethylome in Leukemia and Normal Blood Cells

(W0930-04-27) Novel Blood Pressure Lowering Effects of Statins

(T0930-04-28) ABCB1 and HMGB1 Gene Polymorphism and Adverse Reactions to Carboplatin and Paclitaxel Treatment in Patients with Non-small Cell Lung Cancer

(M0930-04-28) Associations of Polymorphisms of the ABCB1 and ABCC2 Genes with Cisplatin-Induced Nephrotoxicity and Myelosuppression in Patients with Head and Neck Cancer

(W0930-04-28) Enhanced Cytotoxic Effect of Paclitaxel in Combination with Calcipotriol on Human Pancreatic Cancer Cells

(W0930-05-29) Contribution of High-Speed In-Line Inspection to Automated and DoE-Based Development of Tablets

(W0930-05-30) Comparison of Paclitaxel Distribution across CNS and PNS Barriers after Administration of Cremophor EL/Ethanol Solubilized, Albumin-Bound and Micellar Paclitaxel

(M0930-05-30) Dynamic In Vitro Cell Culture Model to Study Pathogenic Interactions in Periodontitis In Flow Using a Lab-on-a-Disc Platform

(M0930-05-31) Assessment of Stability and Erosion Behavior of ASDs by Using VCM Technique

(W0930-05-31) Repurposing Amodiaquine as a Dry Powder Inhaled Formulation for Respiratory Disorders

(W0930-05-32) Repurposing an Antiviral Peptide to Inhibit Tumor-Derived Exosomes for Synergistic Cancer Immunotherapy

(M0930-05-32) Theoretical and Experimental Polymer-Polymer Miscibility Prediction: An Insight to In Vivo Compatibility

(M0930-05-33) Development of a Water-Soluble Mini-Tablet Formulation for Flow Cytometry Applications

(W0930-05-33) Regulation of Rat Hepatic Monocarboxylate Transporter Expression by Sex and Cross-Sex Hormone Treatment

(W1030-04-22) Combination Therapy of Geranylgeranyl Diphosphate Synthase Inhibitor and Fatty Acid Synthase Inhibitor in Multiple Myeloma

(T1030-04-22) Impact of Solvent Choice in the Spray-Freeze-Drying of Insoluble Excipients

(W1030-04-23) Promising Mouse Models for Premetastatic Niche

(M1030-04-23) Using Molecular Probes to Dissect and Control the Energetics of Liquid-Liquid Phase Separation in a Model Intrinsically Disordered Protein System

(T1030-04-24) A Simple and Facile Platform for Semi-Solid Extrusion of Different Formulations Containing a Drug-Loaded Mesoporous Material

(W1030-04-24) Diethyldithiocarbamate Copper Nanoparticle Overcomes Resistance in Cancer Therapy without Inhibiting P-glycoprotein

(M1030-04-24) Synthesis of Rhenium Tricarbonyl Phenformin Complex as an Anticancer Theragnostic Agent and Development of LC-MS/MS Assay for Pharmacokinetic Study

(M1030-04-25) Predictive Model to Determine the Aqueous Solubility of BCS Class IV Drugs in Amorphous Solid Dispersions

(W1030-04-25) The Estimates for the Absorption Rate Constant in Pharmacokinetics and Pharmacometrics Are Wrong: A New Era Based on the Finite Absorption Time Concept Rises

(M1030-04-26) Impact of Host Physiological and Pathological Conditions on the Activity of Gut Microbial Beta-Glucuronidases (GUS) toward Hydrolysis of Flavonoids-Glucoronides

(T1030-04-26) Oral Cavity Permeability Assessment Using Sublingual and Buccal In Vitro Tissue Models

(W1030-04-26) Tigecycline Pharmacokinetics after Intrapulmonary Administration in Mice

(T1030-04-27) Identification of FDA-Approved Drugs Targeting Malonyl Co-A Decarboxylase for the Treatment of Obesity

(M1030-04-27) Neflamapimod Inhibits Endothelial Cell Activation and Leukocyte Adhesion by Inhibiting p38 MAPKα and NF-κB Signaling

(T1030-04-28) Co-administration of Irinotecan with Naturally Occurring Flavonoids Exhibits Synergistic Antitumor Effects on Colon Xenograft Tumors

(M1030-04-28) Comparative Cell Viability Study for Paclitaxel Loaded PLGA-PEG Nanoparticles in Established U-87 and Patient Derived Primary GBM10, GBM39, GBM43 and GBM75 Glioblastoma Cells

(W1030-04-28) Differential Modulation of Endoplasmic Reticulum Calcium Pumps SERCA2 and SERCA3 in T Lymphocytes by Small Molecule Allosteric SERCA Activator CDN1163

(W1030-05-29) Pharmacokinetics of the Glucagon-Like Peptide-1 (GLP-1) Receptor Agonist Semaglutide in Rats

(W1030-05-30) Drug Delivery Optimization and Nutraceutical as Adjuvant with Antiretroviral Therapy to Suppress HIV-1 in CNS Reservoirs

(W1030-05-31) Pericyte Control of Gene Expression in the Brain Endothelium: Implications for Alzheimer’s disease

(W1030-05-32) Use of DEM to Troubleshoot Aesthetic Defects in Pharmaceutical Tablets

(W1030-05-33) Study on the Permeability of Ophthalmic Tissues In Vitro

(M1130-04-22) Mitochondrial Activity and Function are Modulated by KLF2 in Rheumatoid Arthritis

(T1130-04-22) The Effect and Distribution of Amorphous Nanosilica Particle in the Brain and Microglial Cells

(W1130-04-22) Valproic Acid Elevates HIF-1α-mediated CGB Expression and Suppresses Glucose Uptake in BeWo Cells

(M1130-04-23) Gut Microbial Metabolites Effect Intracellular Accumulation of Alzheimer’s disease Amyloid Beta Peptides at the Blood-Brain Barrier Endothelium

(W1130-04-23) Synthesis, Conformational Analysis, and Binding Studies of 6α-mannobiose Glycosides

(T1130-04-23) The Response of an Orthotopic Lung Cancer Xenograft Model to Cisplatin

(M1130-04-24) Collagen Droplet-Based Micro-Bioreactors for High-Throughput Drug Screening

(T1130-04-24) Downregulated Expression Levels of miR-451a and miR-185-5p as Potential Biomarkers for Coronavirus Disease 2019 (COVID-19) Severity

(W1130-04-24) Mebendazole Nanosuspension for the Treatment of Glioblastoma

(T1130-04-25) Extended In Vitro-In Vivo Correlation (IVIVC) Model to Predict the Pharmacokinetics of Ticagrelor Sustained-Release Formulations

(W1130-04-25) Software-Optimized Oligonucleotide Purification with Preparative HPLC/MS

(T1130-04-26) Investigation of a Novel Iron Chelator: A Pharmacokinetic and Pharmacodynamic Study

(W1130-04-26) Peonidin-3-O-Glucoside and Resveratrol Reduce Human hFOB Osteoblast Apoptosis and Alter the Expression of Genes Associated with Apoptosis, Differentiation and Osteoclastogenesis

(T1130-04-27) Anticancer Effects of Proteins and miRNAs Picked out by Proteomic Analysis of NK Cell-Derived EVs in Combination with Carboplatin in Resistant Lung Cancer: Role of PDL1/PD-1, SOD2, PARP, NF-kB and SET

(W1130-04-27) The Effect of MO-OH-Nap Tropolone on Osteosarcoma Cellular Metabolism

(M1130-04-28) Could the Plasmatic miRNAs hsa-miR-4433b-5p, hsa-miR-320b and hsa-miR-16-2-2p Be Biomarkers of Covid-19?

(T1130-04-28) Periplasmic Target Site Penetration Rates of Four β-Lactamase Inhibitors in Klebsiella Pneumoniae Carbapenemase-2 (KPC-2) Producing Klebsiella pneumoniae

(M1130-05-29) Synergistic Anticancer Activity of Cannabinoids and Terpenes in Xenograft Mouse Model of Triple Negative Breast Cancer

(M1130-05-30) A Robust, Viable, and Resource Sparing HPLC-Based logP Method Applied to Common Drugs

(T1130-05-30) Development of a Targeted Peptide-Drug Conjugate for the Treatment of Glioblastoma

(M1130-05-31) Antigen-Specific Tolerogenic Nanodiscs for the Treatment of Experimental Autoimmune Encephalomyelitis

(T1130-05-31) Development and Validation of Quantitative Analysis Method for Testosterone Derivatives in Natural musk(Moschus) Using GC-MS

(T1130-05-32) Global Identification of OATP1B1-Associated Proteins and Implications of Calcineurin Inhibition in Time-Dependent OATP1B1 Inhibition

(M1130-05-32) Targeted Transport of Active Pharmaceutical Ingredients into Adipose Tissue and Liver

(T1130-05-33) High-Density Lipoprotein Mimetic Peptide 4F Reduces Amyloid Beta Peptide Accumulation in the Blood-Brain Barrier Endothelium of Alzheimer’s disease brain

(M1130-05-33) Novel Caffeic Acid Phenethyl Ester (CAPE) Derivatives Inhibit Human Multiple Myeloma Cell Growth

(M1230-04-22) Effect of Lung Cancer Exosomal Galectin-3 Binding Protein on Bone Metastasis

(T1230-04-22) The Paracrine Action of Mutant p53 in Breast Cancer

(M1230-04-23) Molecular Mechanisms Driving Sex-Dependent Cerebrovascular Inflammation in Alzheimer's disease

(M1230-04-24) A Novel Electrospinning System to Fabricate Bi-axial Nanofibers for Developing a Floating Pharmaceutical Dosage Form

(T1230-04-24) Hyaluronic Acid Nanogel Cancer Vaccine: Powerful and Versatile Priming Tool for Combinational T Cell Therapy

(M1230-04-25) Biopharmaceutical Analysis of Synthesized Antibiotic Ester Prodrugs; Ciprofloxacin Isopentanoate, Ciprofloxacin N-Butanoate and Ciprofloxacin Isobutanoate

(M1230-04-26) Flow Cytometry and Confocal Microscopy to Quantify β-lactam Penetration in a Double β-lactamase and Double Efflux Pump Knockout Strain of Acinetobacter baumannii (AB)

(T1230-04-26) Mice Deficient in Interleukin 6 (IL-6) Show Improved Short-Term versus Long Term Memory following Methamphetamine Treatment

(M1230-04-27) Tangerine-Peel-Derived Nanovesicles Alleviate Hepatic Steatosis in Type 2 Diabetic Mice via Regulating Lipid Metabolism and Intestinal Flora Disorder

(M1230-04-28) Impact of In-utero Electronic Cigarette Exposure on Neonatal Neuroimmune and Mitochondrial Function

(M1230-05-29) AI and Experimental-Based Discovery and Preclinical IND-Enabling Studies of Selective BMX Inhibitors for Development of Cancer Therapeutics

(T1230-05-29) Finding the Alternative Path: Formulation Strategies for Sustained Release of Challenging Small Molecule Compounds

(M1230-05-30) Application of Quantitative Models to Systematically Evaluate Factors Impacting Swallowability of Tablets

(T1230-05-30) Enhanced Codelivery of Gefitinib and Azacitidine for Treatment of Metastatic-Resistant Lung Cancer Using Biodegradable Lipid Nanoparticles

(M1230-05-31) Impact of Pre-incubation on BCRP and P-gp Transporter Inhibition in the Membrane Vesicle Assay

(T1230-05-31) Pharmacokinetics and Interspecies Scaling of Semaglutide, a GLP-1 Receptor Agonist

(T1230-05-32) Regulation of OATP1B3 Transport Function via Protein Acetylation

(M1230-05-32) Using a Semi-Mechanistic Model to Predict Efficacious Dosing Regimens and Optimal Drug Design Properties for a LNP-Delivered mRNA UGT1A1 Replacement Therapy in Crigler-Najjar Syndrome Type 1 Patients

(M1230-05-33) Concurrent Regulation of OATP1B1 Transport Function by Protein Phosphorylation and Acetylation: Novel Mechanism Underlying Reduced Function of OATP1B1 c.521T >C Single Nucleotide Polymorphism

(T1230-05-33) Renal Monocarboxylate Transporter Expression in Response to Female Sex and Cross-Sex Hormone Treatment

(T1330-04-22) Cell Culture Media Monitoring in Cell and Gene Therapy Supporting Upstream Bioprocessing

(M1330-04-22) Investigation of Molecular Interactions between Active Pharmaceutical Substances and Polymer Excipients Using 1H-NMR

(T1330-04-23) Discovery of Anti-Transforming Growth Factor β Receptor II (TGFβRII) Cyclic Peptides

(M1330-04-23) The Search for HIV Latency Reversing Selective HDAC3 Inhibitors Through Virtual Screening

(T1330-04-24) Characterization of Particle Disposition following Intranasal Inoculation with a 3D Printed Device

(M1330-04-24) Understanding Mechanisms behind Low Conjugation Efficiencies of Thiol-Maleimide Reactions to Synthesize Antibody-Drug Conjugates

(M1330-04-25) Endothelial Cell-Pericyte Interactions Regulate Brain Glucose Transport

(T1330-04-25) The Impact of Surface Area per Volume Ratio on Drug Transport from Supersaturated Solutions of Ketoconazole

(T1330-04-26) Effect of Omeprazole Administration on the Pharmacokinetics of Oral Extended-Release Nifedipine: Physiologically Based Pharmacokinetic Modeling

(M1330-04-26) Urinary MicroRNAs as Possible Biomarkers of Cisplatin-Induced Nephrotoxicity in Patients with Head and Neck Cancer

(M1330-04-27) Activating 5-HT 1A Receptors as a Treatment for Fragile X Syndrome: A Preclinical Study in Fmr1 Knockout Mice

(T1330-04-27) Effect of Propofol on Lipid Membrane Fluidity and Blood-Brain Barrier Permeability

(T1430-05-29) Chiral Separation of Triacyclglycerols Isomers by Supercritical Fluid Chromatography

(T1430-05-30) The Use of Short 10 mm Columns for Ultra-fast LC-MS Analyses

(T1430-05-31) Analysis of Pharmacogenetic Polymorphism Effect of ABCB1 2677G >T/A Through Molecular Modeling Approach

(M1430-05-31) Effects of Testosterone on Kidney Monocarboxylate Transporter Expression

(M1430-05-32) Tetrahydrocurcumin, a Metabolic By-Product of Curcumin, Shows Neuroprotection: A Potential Therapeutic Metabolite for Neurodegenerative Pathologies

(T1430-05-32) The Printability of an Alginate-Based Hydrogel and Its Compatibility with NIH-3T3 Cells

(M1430-05-33) Barrier Properties of Pharmaceutical Polymers – Novel Applications for Protecting Respiratory Membranes from Pathogens

(T1430-05-33) Engineering Human Liver Spheroids with Biomimetic Nanoscaffolds for Preclinical Test of Drug-Induced Liver Injuries

(T1530-05-29) Discovery of a Deazaflavin Analog as Potent and Selective Inhibitor of Multidrug Resistance-Associated Protein 1 (MRP1)

(M1530-05-29) The Effect of Cancer-Associated Cachexia on the Pharmacokinetics of Extra-vascularly Administered Monoclonal Antibodies

(T1530-05-30) Discovery of Oral Vaccine Adjuvant via Bioanalytical HTS Assays

(M1530-05-30) Metformin Induced-Oxidative Stress Modulates LNCaP Cellular Redox Status and Suppressed Cell Growth

(T1530-05-31) A Novel Dissolution Model to Study the Release and Uptake of Oral Lymphotropic Drug Products

(M1530-05-31) Anti-cancer Sonosensitive DOX-Loaded Liposomes to Avoid Systemic Immunosuppression

(T1530-05-32) Topical Dexpanthenol Modulates Microbially Induced Inflammation in a 3D Corneal Model: A Proteomic Analysis

(M1530-05-33) Advancing Lung Cancer Therapy: Development and Optimization of Lorlatinib Loaded Inhaled Nanostructure Lipid Carriers (NLC) Using Design of Experiment Approach

(T1530-05-33) Characterizing the Pharmacological Mechanism of Agmatine in the Spinal Cord Using Calcium Imaging and NMDA-induced Behavioral Assays

(M0930-05-29) Benchmarking Large Multi-task Machine Learning Models for ADME, Toxicology and Drug Discovery Endpoints

(T1130-05-34) Digestion Is an Important Element for Absorption of Cinnarizine from Supersaturated Lipid-Based Type II Formulations

(M1330-04-28) Permeability of Metformin across the Blood-Brain Barrier: Repurposing a Potential Neurotherapeutic for Ischemic Stroke

(M1430-05-30) High-Throughput 3D Bioprinting of Corneal Stromal Equivalents