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Poster Schedule
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Poster Schedule
All Days
Mon, Oct 23
Tue, Oct 24
Wed, Oct 25
Poster Schedule
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Monday, October 23, 2023
9:30 AM – 10:30 AM
ET
(M0930-01-01) Brain-Targeted Oxytocin Nanoparticles Formulated via Microfluidics for Epilepsy
Favorite
9:30 AM – 10:30 AM
ET
(M0930-01-02) Predicting Compression Behaviors of Mixtures from Those of Individual Components
Favorite
9:30 AM – 10:30 AM
ET
(M0930-01-03) A Bivariate Glass Transition Temperature/Molar Volume Empirical Model Predicts Mechanically-Induced Disordering with High Accuracy
Favorite
9:30 AM – 10:30 AM
ET
(M0930-01-04) Development of a Sustained Release Softgel Dosage Form Based on Polyethylene Oxide Polymer
Favorite
9:30 AM – 10:30 AM
ET
(M0930-01-05) Loratadine Nanosuspension-Loaded In Situ Gel: A Promising Thermo-Responsive Delivery System for the Treatment of Allergic Rhinitis
Favorite
9:30 AM – 10:30 AM
ET
(M0930-01-06) Formulation and Characterization of Ionic Liquid-Containing (IL) Melatonin Orally Dissolving Films (ODFs) for Buccal Drug Delivery
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9:30 AM – 10:30 AM
ET
(M0930-01-07) Three-Dimensional Extrusion Based Bioprinting of Metronidazole Immediate Release Tablets; Impact of Processing Parameters on In Vitro Evaluation
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9:30 AM – 10:30 AM
ET
(M0930-02-08) A Novel Immunization Strategy against Malaria Using Microneedles and Virus-Like Particles Vaccine
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9:30 AM – 10:30 AM
ET
(M0930-02-09) Combating SARS-CoV-2 Variants: Pain-Free Bivalent Intranasal Vaccination Delivery
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9:30 AM – 10:30 AM
ET
(M0930-02-11) Exploring Phenylboronic Acid Conjugated pH-Sensitive Liposomes for Targeted Codelivery of Cisplatin-Chlorambucil Prodrug and Venetoclax for Triple-Negative Breast Cancer Management
Favorite
9:30 AM – 10:30 AM
ET
(M0930-02-12) Intradermal Injection of a Thermoresponsive Polymeric Dexamethasone Prodrug (ProGel-Dex) Ameliorate Dermatitis in an Imiquimod (IMQ)-Induced Psoriasis-Like Mouse Model
Favorite
9:30 AM – 10:30 AM
ET
(M0930-02-13) Predicting Food Effects of Commercial Products Using the Dynamic Gastric Model (DGM)
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9:30 AM – 10:30 AM
ET
(M0930-02-14) T Lymphocyte Proliferation in Response to Microparticulate Vaccine Candidates against H1N1 Flu and
Neisseria
gonorrhea
Pathogens
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9:30 AM – 10:30 AM
ET
(M0930-03-16) New Insight into the Oral Delivery Mechanism of Semaglutide Based on All-atom Molecular Dynamics Simulations
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9:30 AM – 10:30 AM
ET
(M0930-03-18) Film-Coated Hard Capsules for Dry Powder Inhalers: Improving Inhalation Efficiency and In-Use Stability
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9:30 AM – 10:30 AM
ET
(M0930-03-19) The Effect of Controlled After-Melt Cooling Rate on Amorphization Degree of High-Drug Loaded Solid Dispersions of a Poor Glass-Forming Drug
Favorite
9:30 AM – 10:30 AM
ET
(M0930-03-20) Optimization of Roller Compaction Process Parameters for a Poorly Soluble Drug Using Quality by Design Tool
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9:30 AM – 10:30 AM
ET
(M0930-03-21) Bioequivalence Prediction Based on In Vitro Flux Assay through the Example of Aripiprazole
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9:30 AM – 10:30 AM
ET
(M0930-03-51) Boosting Antitumor Immune Response against Breast Cancer Cells Using Doxorubicin and Zinc Oxide Nanoparticles Co-loaded Lipid Nanocarrier
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9:30 AM – 10:30 AM
ET
(M0930-04-23) Beneficial Effects of Trehalose on Mesenchymal Stem Cell-Derived Exosomes
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9:30 AM – 10:30 AM
ET
(M0930-04-24) Design and Synthesis of Conformationally Modulated Rutinose Saccharides and Their Conformational Analysis by NMR
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9:30 AM – 10:30 AM
ET
(M0930-04-25) A Compatibility Test of Two-Piece Hard Capsules and Liquid/Semi-solid Excipients - Part 2
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9:30 AM – 10:30 AM
ET
(M0930-04-26) Sodium Butyrate Decreases VCAM-1 Expression by Inhibiting Stat3/GATA6 Signaling Pathway in Alzheimer’s disease
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9:30 AM – 10:30 AM
ET
(M0930-04-27) High-Resolution Sequencing Comparison of the DNA Methylome and Hydroxymethylome in Leukemia and Normal Blood Cells
Favorite
9:30 AM – 10:30 AM
ET
(M0930-04-28) Associations of Polymorphisms of the ABCB1 and ABCC2 Genes with Cisplatin-Induced Nephrotoxicity and Myelosuppression in Patients with Head and Neck Cancer
Favorite
9:30 AM – 10:30 AM
ET
(M0930-05-30) Dynamic In Vitro Cell Culture Model to Study Pathogenic Interactions in Periodontitis In Flow Using a Lab-on-a-Disc Platform
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9:30 AM – 10:30 AM
ET
(M0930-05-31) Assessment of Stability and Erosion Behavior of ASDs by Using VCM Technique
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9:30 AM – 10:30 AM
ET
(M0930-05-32) Theoretical and Experimental Polymer-Polymer Miscibility Prediction: An Insight to In Vivo Compatibility
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9:30 AM – 10:30 AM
ET
(M0930-05-33) Development of a Water-Soluble Mini-Tablet Formulation for Flow Cytometry Applications
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9:30 AM – 10:30 AM
ET
(M0930-06-36) Elements of Robust Modified Oligonucleotide Extraction through SPE
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9:30 AM – 10:30 AM
ET
(M0930-06-38) Quantitation of Bemnifosbuvir and Metabolites in Human Bronchoalveolar Lavage (BAL) by LC-MS/MS
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9:30 AM – 10:30 AM
ET
(M0930-06-39) Enhanced Pharmacokinetic Bioanalysis of Antibody-Drug Conjugates Using Hybrid Immunoaffinity Capture and Microflow LC-MS/MS
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9:30 AM – 10:30 AM
ET
(M0930-06-40) Increased Throughput for Regulated Bioanalysis with Catch-and-Hold Mode of HPLC Separation with High Sensitivity Mass Spectrometers
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9:30 AM – 10:30 AM
ET
(M0930-06-41) Comparison of Branched DNA (B-DNA) and Polymerase Chain Reaction (RT-qPCR) Method Validation for the Quantification of mRNA Therapeutics in Plasma
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9:30 AM – 10:30 AM
ET
(M0930-08-49) Novel Strategies for Process-Related Impurity Clearance during Biologics Manufacturing
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9:30 AM – 10:30 AM
ET
(M0930-08-50) Design, Development, and Evaluation of Novel Extended-Release Liposomal Topical Cream Formulation of Pregabalin Using Microemulsion Technique for the Treatment of Local Neuropathic Pain
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9:30 AM – 10:30 AM
ET
(M0930-08-51) Peak Shear and the Effect of Kneading Block Geometries on Twin Screw Granulation Process Design
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9:30 AM – 10:30 AM
ET
(M0930-08-53) Advancements in Mini-Tablets: High Drug Loading and Precise Dose Titration
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9:30 AM – 10:30 AM
ET
(M0930-08-54) Use of Granulation and E-Tongue for Taste-Masking of an Orally Disintegrating Tablet (ODT)
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9:30 AM – 10:30 AM
ET
(M0930-08-55) Worsened Punch Sticking by External Lubrication with Magnesium Stearate
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9:30 AM – 10:30 AM
ET
(M0930-09-56) Reliable Sizing of Lipid Nanoparticles in Concentrated Formulations Using Advanced Dynamic Light Scattering
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9:30 AM – 10:30 AM
ET
(M0930-09-57) Identification of Isomerization in IgG1 and Its Impact on Potency: Case Study of a Mab Biosimilar
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9:30 AM – 10:30 AM
ET
(M0930-09-58) Screening Chiral Stationary Phases in Multiple Separation Modes to Identify a Method for the Enantiomeric Separation of Modafinil
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9:30 AM – 10:30 AM
ET
(M0930-09-59) CryoTEM Imaging of Onivyde for Precise Reverse Manufacturing
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9:30 AM – 10:30 AM
ET
(M0930-09-60) Terahertz Pulsed Imaging (TPI) Based Liquid Transport Profiling For the Tablet Disintegration Process Analysis
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9:30 AM – 10:30 AM
ET
(M0930-09-61) Scale-Down Modeling of the Filling Process for Protein-Based Parenteral Drug Products
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9:30 AM – 10:30 AM
ET
(M0930-09-62) A Tactic for Resolving Lactose Matrix Interference with Residual Heptane in GC Analysis of an API cPAD Formulation
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9:30 AM – 10:30 AM
ET
(M0930-10-63) Physiologically Based Pharmacokinetic (PBPK) Modeling of Fexofenadine and Assessment of Transporter DDIs of Fexofenadine with P-gp Inducers and Inhibitors
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9:30 AM – 10:30 AM
ET
(M0930-10-64) Quantification of Oligonucleotide Therapeutics in Plasma Using a Generic Kit-Based Approach
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9:30 AM – 10:30 AM
ET
(M0930-10-65) Prospectively Assessing the Immunogenic Risk of Potential Synthetic Peptide Impurities In Silico Using the What-if Machine (WhIM)
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9:30 AM – 10:30 AM
ET
(M0930-10-66) Masking Strategies for Immune Checkpoint Inhibitors to Decouple Adverse Events in Cancer Treatment
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9:30 AM – 10:30 AM
ET
(M0930-10-67) Past-to-Present Comparison of Repeat Analysis-Related Observations in Pharmacokinetic Bioequivalence Studies Submitted in Abbreviated New Drug Applications
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9:30 AM – 10:30 AM
ET
(M0930-10-68) Focus on Efficacy: In Vitro Tissue Models for Preclinical Research
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9:30 AM – 10:30 AM
ET
(M0930-10-69) Mechanistic Modeling of In Vitro Biopharmaceutic Experiments for a Weakly Dibasic Drug for Incorporation into PBPK Models
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9:30 AM – 10:30 AM
ET
(M0930-11-70) A Comparative Study of In Vitro Itraconazole Drug Release from Amorphous Solid Dispersions (ASDs): Sempera® and Tolsura® under Fed State Conditions
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9:30 AM – 10:30 AM
ET
(M0930-11-71) Characterization of Compression Behavior of Co-processed Excipient for Production of Orally Dispersible Tablets and of Their Blends with Active Ingredient
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9:30 AM – 10:30 AM
ET
(M0930-11-72) Drug-Free Bioresponsive Hydrogel for On-Demand Contraception
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9:30 AM – 10:30 AM
ET
(M0930-11-73) Formulation Optimization of EVX-101, a Novel Gastro-Retentive Prolonged-Release 5-HTP/Low-Dose Carbidopa Tablet
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9:30 AM – 10:30 AM
ET
(M0930-11-74) Mannose Functionalized Chitosan Coated PLGA Nanoparticles for Cannabidiol Delivery to the Brain for the Treatment of Alzheimer’s disease
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9:30 AM – 10:30 AM
ET
(M0930-11-75) Predicting the Stability of Amorphous Formulations Mixtures with Terahertz Spectroscopy
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9:30 AM – 10:30 AM
ET
(M0930-11-76) The Impact of Relative Humidity on In Vitro Permeation Test Method Performance Indicators, J
max
, T
max
and Amount Permeated for Molecule, TER-003
Favorite
9:30 AM – 10:30 AM
ET
(M0930-12-77) Low Dose Compatibility Testing With and Without Surfactant in Polyethylene Terephthalate (PETG), Glass, and Polypropylene Container Types for Large Molecule Analysis
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9:30 AM – 10:30 AM
ET
(M0930-12-79) Effect of Different Neutralizers and Their Concentration on Enteric Coating of Hypromellose Phthalate (HPMCP HP-50) and Drug Release in Various pH
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9:30 AM – 10:30 AM
ET
(M0930-12-80) Development of Oral Bi-layer Tablet of Ruxolitinib
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9:30 AM – 10:30 AM
ET
(M0930-12-82) Interaction of Thermal and Rheological Parameters Critical for the Processability of Polyvinyl Alcohol-Based Systems during Hot Melt Extrusion
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9:30 AM – 10:30 AM
ET
(M0930-02-10) Dissolving Microarray Patches Loaded with Atorvastatin Microparticles for Intradermal Long-Acting Delivery
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9:30 AM – 10:30 AM
ET
(M0930-05-29) Benchmarking Large Multi-task Machine Learning Models for ADME, Toxicology and Drug Discovery Endpoints
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9:30 AM – 10:30 AM
ET
(M0930-08-52) Modern Liquid Chromatographic Gradient Method Allowances Provided by General Chapter, USP Chromatography
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10:30 AM – 11:30 AM
ET
(M1030-01-01) Breaking the Pain Barrier: Innovative Strategies for Administering a Whole Cell Inactivated Microparticulate Gonorrhea Vaccine
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10:30 AM – 11:30 AM
ET
(M1030-01-03) A Case Study on the Applicability of the Refined Developability Classification System to Identify Compounds Suitable for Biowaivers: Voriconazole
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10:30 AM – 11:30 AM
ET
(M1030-01-04) Development of Customizable Swelling Vaginal Rings for Targeted Infection Treatment via 3D Printing
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10:30 AM – 11:30 AM
ET
(M1030-01-05) Thrombocytopenia Protective Quetiapine Hemifumarate-Loaded Nasal Nanoemulgels for Schizophrenia
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10:30 AM – 11:30 AM
ET
(M1030-01-06) Release Tunability of Exemestane from EVA Implants
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10:30 AM – 11:30 AM
ET
(M1030-02-08) A Novel Liposomal Delivery for MicroRNA-497 and Venetoclax in Acute Myeloid Leukemia
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10:30 AM – 11:30 AM
ET
(M1030-02-09) Combinational Approach Using AKT/ERK Dual Inhibitors for Pancreatic Cancer
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10:30 AM – 11:30 AM
ET
(M1030-02-10) Dual Functionalized Liposomal Nanoparticles Can Deliver Plasmid Encoding for Angiotensin II Receptor shRNA to the Brain of Spontaneously Hypertensive Rats to Reduce Blood Pressure
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10:30 AM – 11:30 AM
ET
(M1030-02-11) Exploring the Use of Silicone-Based Microemulsions for Formulating Aesthetically Pleasing Topical Pharmaceuticals: Enhancing Patient Compliance and Product Aesthetics
Favorite
10:30 AM – 11:30 AM
ET
(M1030-02-13) Prediction and Investigation of the Effect of Binders on the Occurrence of Tablet Sticking by Powder Rheology
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10:30 AM – 11:30 AM
ET
(M1030-02-14) A Novel Self-Crosslinkable Hydrogel-Based Matrix Microneedle Patch for Smart Glucagon Delivery
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10:30 AM – 11:30 AM
ET
(M1030-03-17) Enhance Transport of Adenosine Integrated in Lipid Nanoparticles Crossing Reconstructed Human Epidermis
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10:30 AM – 11:30 AM
ET
(M1030-03-18) Formulation of Omeprazole Minitablets with Delayed Release: A Seal and Enteric Polymer Coating Approach
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10:30 AM – 11:30 AM
ET
(M1030-03-19) A Complex Bitter Tale of In Vitro vs. In Vivo Findings
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10:30 AM – 11:30 AM
ET
(M1030-03-20) CBD Solid Dispersion by Spray Drying
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10:30 AM – 11:30 AM
ET
(M1030-03-21) Exploring the Potential of Polyvinyl Acetate Dispersion and PVP-90 to Prevent Alcohol-Induced Dose Dumping in Modified Release Formulations
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10:30 AM – 11:30 AM
ET
(M1030-04-23) Using Molecular Probes to Dissect and Control the Energetics of Liquid-Liquid Phase Separation in a Model Intrinsically Disordered Protein System
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10:30 AM – 11:30 AM
ET
(M1030-04-24) Synthesis of Rhenium Tricarbonyl Phenformin Complex as an Anticancer Theragnostic Agent and Development of LC-MS/MS Assay for Pharmacokinetic Study
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10:30 AM – 11:30 AM
ET
(M1030-04-25) Predictive Model to Determine the Aqueous Solubility of BCS Class IV Drugs in Amorphous Solid Dispersions
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10:30 AM – 11:30 AM
ET
(M1030-04-26) Impact of Host Physiological and Pathological Conditions on the Activity of Gut Microbial Beta-Glucuronidases (GUS) toward Hydrolysis of Flavonoids-Glucoronides
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10:30 AM – 11:30 AM
ET
(M1030-04-27) Neflamapimod Inhibits Endothelial Cell Activation and Leukocyte Adhesion by Inhibiting p38 MAPKα and NF-κB Signaling
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10:30 AM – 11:30 AM
ET
(M1030-04-28) Comparative Cell Viability Study for Paclitaxel Loaded PLGA-PEG Nanoparticles in Established U-87 and Patient Derived Primary GBM10, GBM39, GBM43 and GBM75 Glioblastoma Cells
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10:30 AM – 11:30 AM
ET
(M1030-06-36) Stabilization of Human Cells for RNA Extraction Using Capillary-Mediated Vitrification Process
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10:30 AM – 11:30 AM
ET
(M1030-06-37) Strategies and Case Studies to Develop Ultra-sensitive LC-MS/MS Assays for Quantification of Inhalation Drugs in Human Plasma
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10:30 AM – 11:30 AM
ET
(M1030-06-38) Immunocapture LC-MS/MS Assay for the Biomarker, Troponin Fast (TNNI2) Using a Specific Antibody
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10:30 AM – 11:30 AM
ET
(M1030-06-39) Robust Quantification Method Development for Antisense Oligonucleotide by LC-MS/MS
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10:30 AM – 11:30 AM
ET
(M1030-06-40) Optimizing Detector Settings for Method Scaling-Meeting System Suitability Criteria
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10:30 AM – 11:30 AM
ET
(M1030-08-49) Automated Workflow to Study Microsomal Clearance and Analysis of Metabolites Using Collision-Induced Dissociation and Electron-Activated Dissociation
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10:30 AM – 11:30 AM
ET
(M1030-08-50) Characterizing Protein Aggregation Using Flow Imaging Microscopy with Orthogonal and Complementary Analytical Techniques
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10:30 AM – 11:30 AM
ET
(M1030-08-51) Automated In Vitro Population Bioequivalence for Inhaled Products to Meet the FDA Guidance on Budesonide Using Phoenix® WinNonlin®
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10:30 AM – 11:30 AM
ET
(M1030-08-52) AQbD Method Development for a Venlafaxine Extended-Release Tablets Organic Impurities Procedure
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10:30 AM – 11:30 AM
ET
(M1030-08-54) Benefits of the Structure-Data File (SD File) Format for Knowledge Aided Structured Assessment (KASA) and Cheminformatics in FDA
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10:30 AM – 11:30 AM
ET
(M1030-08-55) Correlating Tablet Performance Differences to Tablet Microstructure Via MFV-SEM and XRM Imaging Coupled with AI Image Analytics
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10:30 AM – 11:30 AM
ET
(M1030-09-56) Investigating In Vitro Transcription of Host Cell and Plasmid DNA Impurities in Recombinant AAV Drug Substances
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10:30 AM – 11:30 AM
ET
(M1030-09-57) Measuring and Controlling Potency of a Targetless Biologic: Study of PEGylated Hemoglobin
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10:30 AM – 11:30 AM
ET
(M1030-09-58) Effects of Tableting Speed, Blending Time, and Feed Frame Shear Sensitivity on Tablet Properties
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10:30 AM – 11:30 AM
ET
(M1030-09-60) A Material Sparing Approach for Predicting Ribbon Solid Fraction at Diverse Roll Compaction Speeds
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10:30 AM – 11:30 AM
ET
(M1030-09-61) Characterization of Stress Induced Amorphous Phase Formation during Tableting Detected by Solid-State NMR – Implications on Stability and Formulation Selection
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10:30 AM – 11:30 AM
ET
(M1030-09-62) Crystallization and Unique Crystal Structures of the Clinical Cyclic Peptide LUNA18
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10:30 AM – 11:30 AM
ET
(M1030-10-63) In Vitro and In Vivo Pharmacokinetics of a Novel B7-H3 Inhibitor (Ni1) for the Treatment of Group 3 Medulloblastoma
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10:30 AM – 11:30 AM
ET
(M1030-10-64) Concentrations and Causal Confounding: Choosing Exposure Measures with Care When Constructing an Exposure-Response Analysis
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10:30 AM – 11:30 AM
ET
(M1030-10-65) Clinical Correlation of Conventional Allometric Scaling Approach for PK Predictions of FcRn Enhanced and Protease Resistant Long-Acting mAbs, TAVO101 and TAVO103
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10:30 AM – 11:30 AM
ET
(M1030-10-66) Integrating Herbal Medicine into Modern Practice: Nonclinical Evaluation of
Cinnamomum cassia
Extract and Extrapolation from Animals to Humans
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10:30 AM – 11:30 AM
ET
(M1030-10-67) Determination of the Concentration of the Drug MG1113 in Human Sodium Citrate Plasma Using a Sandwich Electro Chemiluminescent Immunoassay (ECLIA)
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10:30 AM – 11:30 AM
ET
(M1030-10-68) Plasma Pharmacokinetics and Tissue Disposition of Cefoxitin in an Animal Model of Obesity
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10:30 AM – 11:30 AM
ET
(M1030-10-69) Elucidation of Interaction Mechanisms between Irinotecan and Oroxylin A in Rats through Physiologically Based Pharmacokinetic Modeling
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10:30 AM – 11:30 AM
ET
(M1030-11-70) Controlled Release Edaravone Nanosuspension: A Translational Therapeutic Approach for the Prevention of Preterm Birth
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10:30 AM – 11:30 AM
ET
(M1030-11-71) Dual Functionalized Polymeric Nanoparticles Encapsulating Emtricitabine and Bictegravir for Delivery Across the Blood Brain Barrier for the Management of HIV Associated Neurocognitive Disorders (HAND)
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10:30 AM – 11:30 AM
ET
(M1030-11-72) Guided Assembly of Lymph Node Stromal Cells Using a Biomaterial Formulation
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10:30 AM – 11:30 AM
ET
(M1030-11-73) Manufacturing and Elucidating the Drug Release Mechanisms of Long-Acting Ethylene Vinyl Acetate-Based Implants
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10:30 AM – 11:30 AM
ET
(M1030-11-75) The Impacts of PLGA’s Material Characteristics on the Performance of PLGA-Based Implant Prepared by Hot Melt Extrusion
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10:30 AM – 11:30 AM
ET
(M1030-11-76) Correlation between Material Properties, Extrusion Processing Conditions and Permeability of Etonogestrel in Polyethylene Vinyl Acetate Films
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10:30 AM – 11:30 AM
ET
(M1030-12-77) A Study on the Visible Aggregation of a Peptide Formulation Under Stress Conditions at Manufacturing Fill and Finish Process
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10:30 AM – 11:30 AM
ET
(M1030-12-78) Hydrolysis Kinetics of the Prodrug Dodecyl Nicotinate in Buffered Solutions, and Skin and Liver Homogenates
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10:30 AM – 11:30 AM
ET
(M1030-12-79) Improving Drug Solubility in Solid Oral Formulations Using Low Melting Point Systems
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10:30 AM – 11:30 AM
ET
(M1030-12-80) Enhanced Ocular Delivery of lifitegrast Using New Contact Lens DDS System
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10:30 AM – 11:30 AM
ET
(M1030-12-81) Development of a Platform Coating Approach to Taste Masking Bitter Drugs in Micro-tablets for Pediatric Patients
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10:30 AM – 11:30 AM
ET
(M1030-12-82) Investigation of Rational Selection of Small Molecule Acids in pH-Independent Extended-Release Matrix Tablets of Weakly Basic Drugs
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10:30 AM – 11:30 AM
ET
(M1030-12-83) Application of Hybrid Extracellular Vesicle-Liposome (EV-Lip) to Improve the Encapsulation Efficiency of Antiretroviral Drugs
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11:30 AM – 12:30 PM
ET
(M1130-01-01) Repurposing Neratinib for the Treatment of Triple-Negative Breast Cancer by Nanocrystals Formulation Approach
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11:30 AM – 12:30 PM
ET
(M1130-01-02) Development of Therapeutic Immunoliposome to Deliver Recombinant Human Enzyme for the Treatment of Pompe Disease
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11:30 AM – 12:30 PM
ET
(M1130-01-03) A Clinical Study to Assess the Bioequivalence of Topical Diclofenac Products Using Dermal Open Flow Microperfusion
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11:30 AM – 12:30 PM
ET
(M1130-01-05) Toward Enhanced Stability of mRNA Lipid Nanoparticles
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11:30 AM – 12:30 PM
ET
(M1130-01-06) Formulation and In Vitro Anticancer Activity of Folate Receptor Targeted PLGA Nanoparticles Loaded with Apigenin
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11:30 AM – 12:30 PM
ET
(M1130-01-07) Map the Formulation Space of Lipid Nanoparticles (LNPs) Using Microfluidic Assembly in the Intraperitoneal (IP) Administration of RNA Therapeutics
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11:30 AM – 12:30 PM
ET
(M1130-02-08) The Development and Characterization of Nanocrystal-Loaded Dissolving Microarray Patches for Transdermal Atorvastatin Delivery
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11:30 AM – 12:30 PM
ET
(M1130-02-09) Combining the Dynamic Gastric Model (DGM) with the Biorelevant Gastrointestinal Transfer (BioGIT) System to Evaluate the Performance of Three Nurofen® Ibuprofen Products
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11:30 AM – 12:30 PM
ET
(M1130-02-10) Effect of Binary vs Ternary Systems on Stability and Drug Release Performance of Amorphous Solid Dispersions
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11:30 AM – 12:30 PM
ET
(M1130-02-11) Extended Release Abuse Deterrent Formulation of an Opioid Analgesic
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11:30 AM – 12:30 PM
ET
(M1130-02-12) Machine Learning Predicts Pharmaceutical Inkjet Printing Outcomes
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11:30 AM – 12:30 PM
ET
(M1130-02-14) The Effect of the Edge Activator Combinations in Transethosomal Formulations for Skin Delivery of Thymoquinone
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11:30 AM – 12:30 PM
ET
(M1130-03-15) Synergistic Chemotherapy for Prostate Cancer Mediated by Brusatol and Docetaxel-Loaded Nanoparticles: Cell Cycle Arrest and Apoptosis Mechanisms
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11:30 AM – 12:30 PM
ET
(M1130-03-16) Enteric Functional Ready-to-Fill Capsule Solution from Pre-Clinic to Commercial
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11:30 AM – 12:30 PM
ET
(M1130-03-18) Toward IVIVC for ASDs by Convolution of First Derivative Permeation Profiles
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11:30 AM – 12:30 PM
ET
(M1130-03-19) Improving Bioavailability of Palbociclib Using Amorphous Solid Dispersion
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11:30 AM – 12:30 PM
ET
(M1130-03-20) The Role of MicroCoat™ in Refining Tamoxifen Administration to Mice and Achieving Inducible Cre Recombinase
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11:30 AM – 12:30 PM
ET
(M1130-03-21) Is the pH-LLPS Concentration Profiles follow the Henderson-Hasselbalch Equation?
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11:30 AM – 12:30 PM
ET
(M1130-04-22) Mitochondrial Activity and Function are Modulated by KLF2 in Rheumatoid Arthritis
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11:30 AM – 12:30 PM
ET
(M1130-04-23) Gut Microbial Metabolites Effect Intracellular Accumulation of Alzheimer’s disease Amyloid Beta Peptides at the Blood-Brain Barrier Endothelium
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11:30 AM – 12:30 PM
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(M1130-04-24) Collagen Droplet-Based Micro-Bioreactors for High-Throughput Drug Screening
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11:30 AM – 12:30 PM
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(M1130-04-28) Could the Plasmatic miRNAs hsa-miR-4433b-5p, hsa-miR-320b and hsa-miR-16-2-2p Be Biomarkers of Covid-19?
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11:30 AM – 12:30 PM
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(M1130-05-29) Synergistic Anticancer Activity of Cannabinoids and Terpenes in Xenograft Mouse Model of Triple Negative Breast Cancer
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11:30 AM – 12:30 PM
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(M1130-05-30) A Robust, Viable, and Resource Sparing HPLC-Based logP Method Applied to Common Drugs
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11:30 AM – 12:30 PM
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(M1130-05-31) Antigen-Specific Tolerogenic Nanodiscs for the Treatment of Experimental Autoimmune Encephalomyelitis
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11:30 AM – 12:30 PM
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(M1130-05-32) Targeted Transport of Active Pharmaceutical Ingredients into Adipose Tissue and Liver
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11:30 AM – 12:30 PM
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(M1130-05-33) Novel Caffeic Acid Phenethyl Ester (CAPE) Derivatives Inhibit Human Multiple Myeloma Cell Growth
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11:30 AM – 12:30 PM
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(M1130-06-36) Characterization of Blueberry-Derived Exosomes: New Insights into a Potential Nanomedicine
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11:30 AM – 12:30 PM
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(M1130-06-37) Bioanalytical Assessments of a Novel Approach to Overcome Microsampling Challenges in Rodent Studies
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11:30 AM – 12:30 PM
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(M1130-06-38) Innate Immune Response Modulating Impurities Assay for Assessing Synthetic Semaglutide and Liraglutide
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11:30 AM – 12:30 PM
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(M1130-06-39) PABE: A Novel Enhanced Drug Tolerant Assay Format to Detect Anti-Drug Antibodies in the Presence of High Concentrations of rhAAT-Fc
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11:30 AM – 12:30 PM
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(M1130-06-40) Development and Validation of a Sensitive Hybridization-Electrochemiluminescence (H-ECL) Method for Quantitation of STK-002, an Antisense Oligonucleotide, in Human Serum
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11:30 AM – 12:30 PM
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(M1130-08-49) Identifying and Characterizing the Effect of Critical Processing Parameters in Double Emulsion Poly(lactic-co-glycolic) Acid Microparticle Fabrication
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11:30 AM – 12:30 PM
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(M1130-08-50) A Multicomponent Media Analysis Workflow using Triple Quadrupole Mass Spectrometry during Human Primary T cell Culture
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11:30 AM – 12:30 PM
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(M1130-08-51) Comparative Study of Suitability for Wet Continuous Production Process Using MCC with Different Characteristics
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11:30 AM – 12:30 PM
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(M1130-08-52) Enabling Formulation Development of LAIs Thorough Understanding Critical Formulation Parameters
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11:30 AM – 12:30 PM
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(M1130-08-53) Investigation of Non-specific Adsorption of Lipid Components of the Emulsion-Based Formulations Stored in Glass Vials
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11:30 AM – 12:30 PM
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(M1130-08-54) Mitigation Strategies to Reduce the Risk of the N-nitrosamine Impurity in Drug Products
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11:30 AM – 12:30 PM
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(M1130-08-55) Effects of SDS Quality and Dissolution Medium Warm-Up Time on Dissolution Release of MRTX849 IR Tablets, 200 mg
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11:30 AM – 12:30 PM
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(M1130-09-56) Development of an Industry Ready Cell-Based Potency Method for an Oncolytic Virus Immunotherapy
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11:30 AM – 12:30 PM
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(M1130-09-57) Revisiting UV Spectroscopy for Real-Time Monitoring of Reversible Protein Unfolding
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11:30 AM – 12:30 PM
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(M1130-09-58) NTA Analysis: Linear Range Evaluation for Exosomes
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11:30 AM – 12:30 PM
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(M1130-09-60) Use of Robotics and 3D Printing to Assess In Vitro Adhesive Tack Testing of Transdermal Patches
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11:30 AM – 12:30 PM
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(M1130-09-61) Biofouling Assessment of Zwitterionised Superhydrophilic Polyvinyl Alcohol Hydrogels using
E. coli and S. aureus
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11:30 AM – 12:30 PM
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(M1130-09-62) A Continuous Future: Demonstrating Proof of Concept for Continuous Post-Drying of Pharmaceutical Spray Dried Intermediates
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11:30 AM – 12:30 PM
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(M1130-10-64) Effect of Amounts of DMSO and Incubation Time on BBB-PAMPA Permeability of Drugs with High and Low BBB Permeability
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11:30 AM – 12:30 PM
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(M1130-10-65) A Next Generation Mathematical Model for the In Vitro to Clinical Translation of T-Cell Engagers
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11:30 AM – 12:30 PM
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(M1130-10-66) Pharmacokinetics of Mitragynine, a Kratom Alkaloid, in Pregnant Rats: Implications for Maternal and Fetal Health
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11:30 AM – 12:30 PM
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(M1130-10-67) Model Based Analysis for Determining Bioequivalence of Metronidazole Topical Cream
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11:30 AM – 12:30 PM
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(M1130-10-68) Influence of Bovine Serum Albumin on Colonic Mucus Permeation and Solubility of Celecoxib and Naproxen in Fasted State Simulated Colonic Fluids
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11:30 AM – 12:30 PM
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(M1130-10-69) Tissue Engineered Human 3D Tumor Model Portfolio Reflecting In Vivo Characteristics for Eficacy Assessment of Preclinical Anti-cancer Therapy In Vitro
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11:30 AM – 12:30 PM
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(M1130-11-70) A DoE Approach to Study the Influence of TSWG Process Parameters on the Characteristics of Granules and Tablets
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11:30 AM – 12:30 PM
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(M1130-11-71) A Kupffer Cell-Targeting Nanoparticle System to Mitigate Alcohol-Related Liver Disease (ALD)
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11:30 AM – 12:30 PM
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(M1130-11-72) Effect of Tetanus Toxoid Fragment C (TT
c
) and Transferrin (T
f
) Functionalized Liposomal Nanoparticle Encapsulating Plasmid APOE2 for the Treatment of Alzheimer’s Disease
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11:30 AM – 12:30 PM
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(M1130-11-73) Hydroxypropyl-β-cyclodextrin (HPBCD) in Insoluble Drug-Loaded Nanoparticles Dissolution Studying: A New Approach to Overcoming Sink Limitations
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11:30 AM – 12:30 PM
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(M1130-11-74) Manufacturing of Medicated Contact Lenses Using Inkjet Printing
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11:30 AM – 12:30 PM
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(M1130-11-75) Radiation-Induced Tumor Penetration of Mesoporous Silica Nanoparticles for Enhanced Treatment of Ovarian Cancer Peritoneal Metastasis
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11:30 AM – 12:30 PM
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(M1130-12-77) Stabilization and Formulation Development of Lipid Nanoparticles (LNPs) for Nucleic Acid-Based Therapeutics
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11:30 AM – 12:30 PM
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(M1130-12-78) Mechanistic Insights of Luteolin Loaded Elastic Liposomes for Transdermal Delivery: HSPiP Predictive Parameters and Instrumental Based Evidence
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11:30 AM – 12:30 PM
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(M1130-12-79) Use of Resonant Acoustic Technology for Ultra-Low Dose Blending in a Single-Step Mixing Process
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11:30 AM – 12:30 PM
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(M1130-12-80) Preparation and Characterization of Alectinib Amorphous Solid Dispersion Using a Novel Polymer Apinovex™ to Enhance Solubility and Dissolution
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11:30 AM – 12:30 PM
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(M1130-12-81) Detection of Voriconazole Nanoaggregates in Rat Lung by Mass Spectrometry Imaging after Dry Powder Insufflation
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11:30 AM – 12:30 PM
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(M1130-12-82) PVA as Binder in Continuous Twin-Screw Granulation
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11:30 AM – 12:30 PM
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(M1130-12-83) A Data Based Approach to Selection of Bioavailability Enhancement Strategy Using New Simultaneous Dissolution-Flow Through Permeability for Formulation Development
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12:30 PM – 1:30 PM
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(M1230-01-02) Formulation Development and Evaluation of Cannabidiol Oral Film Using Antisolvent and Solvent Casting Approaches
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12:30 PM – 1:30 PM
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(M1230-01-03) Characterization of Drug Release from a Blended Biodegradable Polymeric Film Using a Central Composite Design
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12:30 PM – 1:30 PM
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(M1230-01-05) Mechanistic Analysis of Excessive Viscosity Increase of Drug Nanosuspension during Wet Milling
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12:30 PM – 1:30 PM
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(M1230-01-06) Screening of Synergistic Combination of Ferroptosis-Inducing Drugs and Development of Targeted PLGA Nanoparticles for Improved Anti-Cancer Therapy
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12:30 PM – 1:30 PM
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(M1230-01-07) Does Elastomer QbD Approach Benefit the E&L Risk Profile for Drug Compatibility? A Comparative Leachables Simulation Study at 12M for Stoppers
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12:30 PM – 1:30 PM
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(M1230-02-08) A Quality-by-Design Approach for the Development of Inhalable Dry Powder Containing Dual Drug-Loaded Polymeric Nanoparticles for Pulmonary Tuberculosis Treatment
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12:30 PM – 1:30 PM
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(M1230-02-09) Comparison of Controlled-Release Performance between Carrageenan and Several Other Hydrophilic Polymers
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12:30 PM – 1:30 PM
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(M1230-02-10) Effect of Homotypic vs Heterotypic Interactions on the Cellular Uptake of Extracellular Vesicles
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12:30 PM – 1:30 PM
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(M1230-02-11) Formulation and Biological Evaluation of Spray Dried Microparticles Loaded with LL37 Antimicrobial Peptide
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12:30 PM – 1:30 PM
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(M1230-02-12) Management of Type-2 Diabetes via Exploration of Transdermal Delivery Strategies for Linagliptin
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12:30 PM – 1:30 PM
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(M1230-02-13) Preparation and Evaluation of Co-Amorphous Formulations of Telmisartan - Amino Acids as a Potential Method for Solubility and Dissolution Enhancement
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12:30 PM – 1:30 PM
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(M1230-02-14) The Influence of Coating Parameters on Transparency of Semi-permeable Membrane Coating of Push-Pull Osmotic Pump Tablets
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12:30 PM – 1:30 PM
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(M1230-03-15) Fabrication of Eco-Benign Isoniazid-Loaded-Silver Nanoparticles: A Novel Approach against Multidrug-Resistant Tuberculosis
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12:30 PM – 1:30 PM
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(M1230-03-16) Systemic Delivery of Paclitaxel by Find-Me Nanoparticles Activates Anti-tumor Immunity and Eliminates Tumors
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12:30 PM – 1:30 PM
ET
(M1230-03-17) Strategies for Producing Clinical and Commercial RNA-LNP Drug Products
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12:30 PM – 1:30 PM
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(M1230-03-18) Formulation of an Inhalable Nanoemulsion Prepared with a Deep Eutectic Solvent of Pirfenidone and Citric Acid
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12:30 PM – 1:30 PM
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(M1230-03-19) Preparation of Osmotic Tablets Using a Direct-to-Hopper Formulated Push Layer Based on Polyethylene Oxide
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12:30 PM – 1:30 PM
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(M1230-03-20) Drug Product Attributes as an Effect of Formulation Composition of Vardenafil HCl Tablets Produced by the Mixture of the Coprocessed Excipient versus a Similar Spray-Dried Lactose Blend
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12:30 PM – 1:30 PM
ET
(M1230-03-21) Should Amorphous Dispersions Always Be Used as a Formulation Development Strategy?
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12:30 PM – 1:30 PM
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(M1230-04-22) Effect of Lung Cancer Exosomal Galectin-3 Binding Protein on Bone Metastasis
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12:30 PM – 1:30 PM
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(M1230-04-23) Molecular Mechanisms Driving Sex-Dependent Cerebrovascular Inflammation in Alzheimer's disease
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12:30 PM – 1:30 PM
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(M1230-04-24) A Novel Electrospinning System to Fabricate Bi-axial Nanofibers for Developing a Floating Pharmaceutical Dosage Form
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12:30 PM – 1:30 PM
ET
(M1230-04-25) Biopharmaceutical Analysis of Synthesized Antibiotic Ester Prodrugs; Ciprofloxacin Isopentanoate, Ciprofloxacin N-Butanoate and Ciprofloxacin Isobutanoate
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12:30 PM – 1:30 PM
ET
(M1230-04-26) Flow Cytometry and Confocal Microscopy to Quantify β-lactam Penetration in a Double β-lactamase and Double Efflux Pump Knockout Strain of
Acinetobacter baumannii (AB)
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12:30 PM – 1:30 PM
ET
(M1230-04-27) Tangerine-Peel-Derived Nanovesicles Alleviate Hepatic Steatosis in Type 2 Diabetic Mice via Regulating Lipid Metabolism and Intestinal Flora Disorder
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12:30 PM – 1:30 PM
ET
(M1230-04-28) Impact of In-utero Electronic Cigarette Exposure on Neonatal Neuroimmune and Mitochondrial Function
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12:30 PM – 1:30 PM
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(M1230-05-29) AI and Experimental-Based Discovery and Preclinical IND-Enabling Studies of Selective BMX Inhibitors for Development of Cancer Therapeutics
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12:30 PM – 1:30 PM
ET
(M1230-05-30) Application of Quantitative Models to Systematically Evaluate Factors Impacting Swallowability of Tablets
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12:30 PM – 1:30 PM
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(M1230-05-31) Impact of Pre-incubation on BCRP and P-gp Transporter Inhibition in the Membrane Vesicle Assay
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12:30 PM – 1:30 PM
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(M1230-05-32) Using a Semi-Mechanistic Model to Predict Efficacious Dosing Regimens and Optimal Drug Design Properties for a LNP-Delivered mRNA UGT1A1 Replacement Therapy in Crigler-Najjar Syndrome Type 1 Patients
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12:30 PM – 1:30 PM
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(M1230-05-33) Concurrent Regulation of OATP1B1 Transport Function by Protein Phosphorylation and Acetylation: Novel Mechanism Underlying Reduced Function of OATP1B1 c.521T >C Single Nucleotide Polymorphism
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12:30 PM – 1:30 PM
ET
(M1230-06-36) Method Development and Validation of a Sensitive and Robust Human Serum PK Immunoassay for a Novel Bispecific Antibody by an Automated Microfluidic System
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12:30 PM – 1:30 PM
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(M1230-06-37) Development of a Sensitive and Specific Phospho-Tau 217 [Tau (pT217)] Biomarker Assay for Alzheimer’s Disease in Plasma and Serum
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12:30 PM – 1:30 PM
ET
(M1230-06-38) Evaluation of Free vs Total Measurement of Monoclonal Antibody-Based Therapeutics with Low Binding Affinity to Soluble Target
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12:30 PM – 1:30 PM
ET
(M1230-06-40) Cetuximab-Based Proteolysis Targeting Chimera for Effectual Downregulation of NSCLC with Varied EGFR Mutations
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12:30 PM – 1:30 PM
ET
(M1230-08-49) Physical Evaluation of a Late Appearing Polymorph of Ritonavir Form III
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12:30 PM – 1:30 PM
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(M1230-08-51) Elucidating the Effect of Processing Temperature and Acid Hydrolysis on Molecular Weight Distribution of Carrageenan
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12:30 PM – 1:30 PM
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(M1230-08-52) Quality Assessment of Polysorbates 80 and 20 Pharmaceutical Raw Materials by Measuring Fatty Acids Composition using HPLC with Mass Detection
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12:30 PM – 1:30 PM
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(M1230-08-53) An Investigation of Robust Sample Preparation on an Automated Tablet Processing Workstation, and Lessons Learned
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12:30 PM – 1:30 PM
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(M1230-08-54) Optimizing Medication Regimens with Robo-Pharmacist: A Cost-Effective Approach to Reduce Polypharmacy and Improve Adherence
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12:30 PM – 1:30 PM
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(M1230-09-56) Trace Level Quantification of Nitrosamine Impurities in Tuberculosis Medicines by LC-MS/MS
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12:30 PM – 1:30 PM
ET
(M1230-09-57) A Workflow for Purity Determination, Intact Mass Measurement, and MS/MS Sequencing of Oligonucleotide Impurities Detected in Synthetic Oligonucleotides
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12:30 PM – 1:30 PM
ET
(M1230-09-58) Photo-Stability of Peptides Exposed to LED, Fluorescent or UV Light in Liquid and Solid Formulations
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12:30 PM – 1:30 PM
ET
(M1230-09-59) Artificial Intelligence Based Particle Characterization for Predictive Insight of Drug Product Quality and Performance
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12:30 PM – 1:30 PM
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(M1230-09-60) Advantage and Challenges of PROTAC Research, Development and Manufacturing
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12:30 PM – 1:30 PM
ET
(M1230-09-61) Predicting Granule and Tablet Properties Using In-Line Measurements and Evolutionary Equation Discovery
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12:30 PM – 1:30 PM
ET
(M1230-09-62) Detecting Low-Level Crystallinity in ASD-Like Samples Using SSNMR Techniques
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12:30 PM – 1:30 PM
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(M1230-10-63) Characterization of Preclinical In Vitro and In Vivo Pharmacokinetics Properties for JNJ-64619178, a New Therapeutic for the Treatment of Medulloblastoma
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12:30 PM – 1:30 PM
ET
(M1230-10-64) PBPK Modeling Coupled with Biorelevant Dissolution to Forecast the Oral Performance of Amorphous Solid Dispersion Formulations
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12:30 PM – 1:30 PM
ET
(M1230-10-65) Pharmacokinetic Characterization of a Novel COVID-19 Inhibitor OJT010 in a Rat Model
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12:30 PM – 1:30 PM
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(M1230-10-66) Assessment of the Effect of Resmetirom, a Liver-Directed, Orally Active, Selective Thyroid Hormone Receptor-β Agonist, on the Pharmacokinetics and Pharmacodynamics of Warfarin in Healthy Subjects
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12:30 PM – 1:30 PM
ET
(M1230-10-67) Rivaroxaban Pharmacokinetics after Single Oral Dose in Obese Subjects: An Open-Label Controlled Clinical Trial
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12:30 PM – 1:30 PM
ET
(M1230-10-68) Ultrasmall Nanoprobes for Fluorescence-Guided Surgical Resection of Peritoneally Disseminated Tumors
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12:30 PM – 1:30 PM
ET
(M1230-10-69) Population Pharmacokinetics of Enrofloxacin and Florfenicol in the Giant Danio (Devario aequipinnatus) following Oral and Bath Administration
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12:30 PM – 1:30 PM
ET
(M1230-11-70) A Nature Inspired Octopus-Shaped 3D Printed Floating Drug Delivery System
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12:30 PM – 1:30 PM
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(M1230-11-71) Design and Development of Nanoformulation of GMC1, a Novel Agent for the Treatment of Castration Resistant Prostate Cancer
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12:30 PM – 1:30 PM
ET
(M1230-11-72) Encapsulation of Zidovudine via Spray-Drying for Taste-Masking for Incorporation into an Orally Dispersible Film
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12:30 PM – 1:30 PM
ET
(M1230-11-73) Impact of Clean Label Lubricant Inclusion Level and Mixing Time on Tablet Properties
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12:30 PM – 1:30 PM
ET
(M1230-11-74) Mass Transport Analysis of Solute Transport through Lipophilic Membranes
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12:30 PM – 1:30 PM
ET
(M1230-11-75) Rational Development of Fingolimod-Curcumin Nanosuspension as a Potential Intranasal Neuroprotective Therapy after Ischemic Stroke
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12:30 PM – 1:30 PM
ET
(M1230-11-76) Topical Ocular Administration of Hydrogen Sulfide Donor: Assessment of Permeability through Isolated Bovine Cornea Ex Vivo
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12:30 PM – 1:30 PM
ET
(M1230-12-77) Cellular Uptake and Real-Time ROS Sensing of Doxorubicin-Loaded Self-Assembled Albumin Nanoparticles Using Liver Bilayer Microfluidic Chip System
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12:30 PM – 1:30 PM
ET
(M1230-12-79) Characterization and Performance of 60% Drug Loaded Freeze-Dried Amorphous Nanoparticle Tablet of a BCS IV Compound: ABT-530
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12:30 PM – 1:30 PM
ET
(M1230-12-80) Formulation Development and Characterization of Parenteral Nicardipine HCl Product for Intrathecal Administration
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12:30 PM – 1:30 PM
ET
(M1230-12-81) Ciprofloxacin-Loaded Albumin Nanoparticles as a New Strategy for the Treatment of Urinary Tract Infections and Catheter-Associated Urinary Tract Infections
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12:30 PM – 1:30 PM
ET
(M1230-12-82) Impact of Extra Components Added to an All-in-One Coprocessed Excipient to Obtain a Better Processability of Cohesive and Poor Flowing Hydrochlorothiazide
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12:30 PM – 1:30 PM
ET
(M1230-12-78) Disruption of Octreotide Interactions with the Bile Acid-Phospholipid Mixed Micelles Using Bile Acid Sequestrants
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1:30 PM – 2:30 PM
ET
(M1330-01-02) Drug Crystal Growth Rate Decreases in the Presence of Coexistent Drug-Polymer Halogen and Hydrogen Bonds
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1:30 PM – 2:30 PM
ET
(M1330-01-03) Formulation Testing of TiO2-Free Film Coating Alternatives from Three Film Coat Vendors
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1:30 PM – 2:30 PM
ET
(M1330-01-04) Characterizing the Drug Gastrointestinal Transfer Process after Disintegration of Solid Dose Units in the Fed State
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1:30 PM – 2:30 PM
ET
(M1330-01-05) Mixing Differences during Preparation Methods have Implications on Successful Formation of Amorphous Solid Dispersions
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1:30 PM – 2:30 PM
ET
(M1330-01-07) Understanding the Relationship Between In Vitro Nasal Spray Characteristics and Intranasal Deposition in the Adult and Pediatric Populations
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1:30 PM – 2:30 PM
ET
(M1330-02-08) A Single-Step Extrusion Process for Formulation Development of Self-Emulsifying Granules for Oral Delivery of a BCS Class IV Drug
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1:30 PM – 2:30 PM
ET
(M1330-02-09) Computational Prediction of Initial Dissolution Performance after Co-milling with PVP
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1:30 PM – 2:30 PM
ET
(M1330-02-11) Formulation and Characterization of Non-invasive Nebulization Based Antiviral Drug, NSF207 Loaded Pegylated Nanoliposomal Suspension Product for Treatment of COVID-19
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1:30 PM – 2:30 PM
ET
(M1330-02-13) Preparation and Optimization of Piperine Nanoparticles for Its Intranasal Delivery
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1:30 PM – 2:30 PM
ET
(M1330-03-15) Effect of Atomic Layer Coatings on the Stability of Solid Myoglobin Formulations
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1:30 PM – 2:30 PM
ET
(M1330-03-16) Mutant mRNA Encapsulated Aptamer Conjugated-Lipid Nanoparticles for Targeting Heart Cells
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1:30 PM – 2:30 PM
ET
(M1330-03-17) Performance Evaluation of Different Diluents for the Direct Compression of Acetaminophen Tablets
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1:30 PM – 2:30 PM
ET
(M1330-03-18) Crafting Lipid-Polymer Nanoparticles of HDAC Inhibitors for the Treatment of Retinitis Pigmentosa
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1:30 PM – 2:30 PM
ET
(M1330-03-19) A New Solid Dispersion Modelling Framework for In Vitro and In Vivo Oral Absorption Anticipation Adapted to pH-Sensitive Matrices
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1:30 PM – 2:30 PM
ET
(M1330-03-20) Development of Various Formulation Strategies/Approaches for an Extended Release of a Non-opioid Narcotic for the Treatment of Acute/Chronic Pain
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1:30 PM – 2:30 PM
ET
(M1330-03-21) Developing Degradable Microparticles for the Delivery of Inactivated H1N1 Virus and NKT Cell Agonist for Single Dose Vaccination
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1:30 PM – 2:30 PM
ET
(M1330-04-22) Investigation of Molecular Interactions between Active Pharmaceutical Substances and Polymer Excipients Using 1H-NMR
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1:30 PM – 2:30 PM
ET
(M1330-04-23) The Search for HIV Latency Reversing Selective HDAC3 Inhibitors Through Virtual Screening
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1:30 PM – 2:30 PM
ET
(M1330-04-24) Understanding Mechanisms behind Low Conjugation Efficiencies of Thiol-Maleimide Reactions to Synthesize Antibody-Drug Conjugates
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1:30 PM – 2:30 PM
ET
(M1330-04-25) Endothelial Cell-Pericyte Interactions Regulate Brain Glucose Transport
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1:30 PM – 2:30 PM
ET
(M1330-04-26) Urinary MicroRNAs as Possible Biomarkers of Cisplatin-Induced Nephrotoxicity in Patients with Head and Neck Cancer
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1:30 PM – 2:30 PM
ET
(M1330-04-27) Activating 5-HT 1A Receptors as a Treatment for Fragile X Syndrome: A Preclinical Study in Fmr1 Knockout Mice
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1:30 PM – 2:30 PM
ET
(M1330-06-36) Determination of Microdystrophin (h-µD5) via Signature Peptide Analysis in Muscle Tissue by LC-MS/MS
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1:30 PM – 2:30 PM
ET
(M1330-06-38) Comparison of Manual and Automated Nucleic Acid Extraction Methods
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1:30 PM – 2:30 PM
ET
(M1330-06-39) Regulatory Perspective of Considerations in Endogenous Therapeutic Analyte Bioanalysis
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1:30 PM – 2:30 PM
ET
(M1330-06-40) A Comprehensive Bioanalytical Strategy of In Vivo Studies for RNAi Therapeutics in Early Discovery
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1:30 PM – 2:30 PM
ET
(M1330-08-49) CryoTEM Characterization of Vaccine Materials in Development
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1:30 PM – 2:30 PM
ET
(M1330-08-50) The Effect of Sampling Cannula on In Vitro Dissolution Testing with USP Paddle Method
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1:30 PM – 2:30 PM
ET
(M1330-08-51) Moisture Activated Dry Granulation: A Sustainable Process with Excipients and Process Consideration
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1:30 PM – 2:30 PM
ET
(M1330-08-52) Optimization of USP Method for Quantitation of Beta Glucan Using a High-Performance Liquid Chromatography and Adapting to a Low Strength Semisolid Dosage Form
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1:30 PM – 2:30 PM
ET
(M1330-08-53) Better Together: Thermally Unstable Drug Granulated Using a Thermal Process?
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1:30 PM – 2:30 PM
ET
(M1330-08-54) Amorphous Solid Dispersion Physical Stability: Historical Examples and Shelf-Life Assessment
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1:30 PM – 2:30 PM
ET
(M1330-08-55) Understanding Release Mechanism and Development of Accelerated Release Tests for Long-Term Intrauterine Systems
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1:30 PM – 2:30 PM
ET
(M1330-09-56) Lipid Nanoparticle Impurity Monitoring Using Single Quadrupole Mass Detection for Regulated Environments
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1:30 PM – 2:30 PM
ET
(M1330-09-57) Unveiling the Impact of Surface Chemistry on Adsorption of a Therapeutic Monoclonal Antibody Using a Quartz Crystal Microbalance
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1:30 PM – 2:30 PM
ET
(M1330-09-58) Impact of Alternative Lubricants on Tablet Parameters Approaching the Over-Lubrication Problems in Continuous Direct Compression Processes
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1:30 PM – 2:30 PM
ET
(M1330-09-59) Development of Iterative Optimization Technology Algorithms with a Small-Scale Feed Frame Simulator: Stagnant vs. Dynamic Pure Component Spectra
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1:30 PM – 2:30 PM
ET
(M1330-09-60) Compendial Strategy to Define Composition and Quality of Polysorbates
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1:30 PM – 2:30 PM
ET
(M1330-09-61) Demonstration of MicroCoat
TM
Scalability: A Fixed Dose Combination of Taste Masked Artesunate-Amodiaquine Micropellets for Malaria Treatment in Paediatrics
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1:30 PM – 2:30 PM
ET
(M1330-09-62) A Twin-Screw Melt Coating and Granulation Approach for High Dose Formulations with any Desired Release Profile
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1:30 PM – 2:30 PM
ET
(M1330-10-63) Effect of pH on Metabolite Profiling and Identification of GalNAc Conjugated siRNA in In Vitro Metabolic System
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1:30 PM – 2:30 PM
ET
(M1330-10-64) Evaluation of In Vitro Protein Binding of STK-001, an Antisense Oligonucleotide, in Plasma and Cerebrospinal Fluid
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1:30 PM – 2:30 PM
ET
(M1330-10-65) Quantifying Clinical Trial Diversity of New Drugs Approved by the FDA
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1:30 PM – 2:30 PM
ET
(M1330-10-66) Case Study: Assessing Innovator vs. Biosimilar mAb Stability to Minimize Immunogenic Risk
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1:30 PM – 2:30 PM
ET
(M1330-10-67) Population Pharmacokinetic Model of Tacrolimus in Brazilian Bone Marrow Transplantation Patients: A Tool for Dosing Regimen Optimization
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1:30 PM – 2:30 PM
ET
(M1330-11-70) A Novel Approach to Formulation Screening of High Concentration Recombinant Human Heparan-N-Sulfatase (rhHNS) Using High-Throughput Devices
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1:30 PM – 2:30 PM
ET
(M1330-11-71) Design and Evaluation of Colon-Targeted Dexamethasone Solid Dispersions for Inflammatory Bowel Disease
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1:30 PM – 2:30 PM
ET
(M1330-11-72) Engineering Gefitinib-Loaded Inhalable Solid Lipid Nanoparticles Using an Organic Solvent-Free Homogenization Method for the Treatment of Non-small Cell Lung Cancer
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1:30 PM – 2:30 PM
ET
(M1330-11-73) Impact of Core Excipient Selection to Improve the Stability of a Moisture Sensitive Drug, Acetylsalicylic Acid
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1:30 PM – 2:30 PM
ET
(M1330-11-74) Mechanism and Generality of the Tabletability Flip Phenomenon
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1:30 PM – 2:30 PM
ET
(M1330-11-75) Reversible, Covalent DNA Condensation Approach via Chemical Linkers for Enhanced Gene Delivery to Nucleus
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1:30 PM – 2:30 PM
ET
(M1330-11-76) Triggering Mucosal Immunity: An Intranasal Combination Vaccine for COVID-19 and Influenza
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1:30 PM – 2:30 PM
ET
(M1330-12-77) Dual Functionality of Poloxamer 188 in Freeze Dried Protein Formulations: A Stabilizer in Frozen Solution and a Bulking Agent
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1:30 PM – 2:30 PM
ET
(M1330-12-78) A Novel Approach for Targeted Pulmonary Delivery of Thymoquinone as Dry Powder Inhaler (DPI)
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1:30 PM – 2:30 PM
ET
(M1330-12-80) Development of a Novel Therapeutic Contact Lens with the Embedded-Drug Chamber as an Ophthalmic Drug Delivery System for Dry Eye Syndrome
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1:30 PM – 2:30 PM
ET
(M1330-12-81) Development of Nanofiber-Based, Anti-proliferative Sutures for Glaucoma Surgery
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1:30 PM – 2:30 PM
ET
(M1330-12-82) Unlocking the Potential of Co-processed Excipient and algorithm-based tool for Direct Compression Tablet Manufacturing
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1:30 PM – 2:30 PM
ET
(M1330-12-83) Physical Stability of Amorphous Pharmaceutical Formulations Insights into Crystallization Behavior
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1:30 PM – 2:30 PM
ET
(M1330-04-28) Permeability of Metformin across the Blood-Brain Barrier: Repurposing a Potential Neurotherapeutic for Ischemic Stroke
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2:30 PM – 3:30 PM
ET
(M1430-01-01) Drug Loading Efficiency of a Topical Anorectal Wipes: A Wipe Impregnation Study
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2:30 PM – 3:30 PM
ET
(M1430-01-03) Fusogenic Liposomes as an Approach to Enhance the Efficacy of Antimicrobials
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2:30 PM – 3:30 PM
ET
(M1430-01-04) Shear-Induced Crystallization of Amorphous Indomethacin
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2:30 PM – 3:30 PM
ET
(M1430-01-05) Cisplatin-Loaded Dendritic Mesoporous Silica Nanoparticles for Improved Drug Delivery to Ovarian Cancer Metastasis
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2:30 PM – 3:30 PM
ET
(M1430-01-06) Multi-functionalized Cationic Chitosan Polymeric Micelles for pVGF Delivery to the Brain through the Intranasal Route
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2:30 PM – 3:30 PM
ET
(M1430-01-07) A Novel Octreotide Conjugated PEGylated Liposomal Paclitaxel for Targeted Pancreatic Cancer Treatment
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2:30 PM – 3:30 PM
ET
(M1430-02-08) A Thermosensitive Hydrogel Formulation of Phage and Colistin Combination for Management of Multidrug-Resistant
Acinetobacter baumannii
Wound Infection
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2:30 PM – 3:30 PM
ET
(M1430-02-09) Co-solvents for Microemulsion Formulations containing Ethoxylated Castor Oils for Transdermal Drug Delivery
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2:30 PM – 3:30 PM
ET
(M1430-02-10) Effects of Monomer on PLGA Based Long-Acting Injectables’ Release and Stability
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2:30 PM – 3:30 PM
ET
(M1430-02-11) Formulation and Evaluation of Prochlorperazine Maleate Sustained Release Mucoadhesive Buccal Films Using Hot Melt Extrusion
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2:30 PM – 3:30 PM
ET
(M1430-02-12) Microfluidics Generated Aspirin Loaded Albumin Nanoparticles for Targeted Brain Delivery in the Treatment of Ischemic Stroke
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2:30 PM – 3:30 PM
ET
(M1430-02-13) Preparation of Ketoprofen Polymer Based Solid SEDDS Using Twin Screw Melt Granulation to Improve the Solubility and Permeability
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2:30 PM – 3:30 PM
ET
(M1430-02-14) Transdermal Delivery of Cannabidiol from Marketed Cannabidiol Patches
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2:30 PM – 3:30 PM
ET
(M1430-03-15) Development of 3D Printable Inks for Protein Delivery
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2:30 PM – 3:30 PM
ET
(M1430-03-16) Solubility Enhancement of Atorvastatin Calcium Trihydrate by Melt Extrusion
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2:30 PM – 3:30 PM
ET
(M1430-03-17) Optimizing Microfluidic Process Parameters and Lipid-Cholesterol Composition for Lysozyme-Loaded Liposome Preparation
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2:30 PM – 3:30 PM
ET
(M1430-03-18) Volumetric Printing and Non-destructive Dose Verification of Water-Soluble Vat Photopolymerized Tablets Based on Supramolecular Chemistry
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2:30 PM – 3:30 PM
ET
(M1430-03-19) Antimicrobial and Angiogenic Silver Nanoparticles and Verapamil Double-Layered Electrospun/3D Printed Wound Healing Patch for Accelerated Wound Healing
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2:30 PM – 3:30 PM
ET
(M1430-03-20) Mini Tablets as a Compliant and Flexible Pediatrics Delivery System
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2:30 PM – 3:30 PM
ET
(M1430-03-21) Computational Support to Identify Ternary Solid Dispersions of Hydroxypropyl Cellulose and Small Molecular Additives to Stabilize Challenging Drugs
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2:30 PM – 3:30 PM
ET
(M1430-05-31) Effects of Testosterone on Kidney Monocarboxylate Transporter Expression
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2:30 PM – 3:30 PM
ET
(M1430-05-32) Tetrahydrocurcumin, a Metabolic By-Product of Curcumin, Shows Neuroprotection: A Potential Therapeutic Metabolite for Neurodegenerative Pathologies
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2:30 PM – 3:30 PM
ET
(M1430-05-33) Barrier Properties of Pharmaceutical Polymers – Novel Applications for Protecting Respiratory Membranes from Pathogens
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2:30 PM – 3:30 PM
ET
(M1430-06-36) Qualification of a Neurology 2-Plex B (Nf-L, GFAP) Quanterix Simoa® Assay Using a Novel Approach
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2:30 PM – 3:30 PM
ET
(M1430-06-37) Toward Development of a New QCM-D Based Method for Rapid Detection of a Novel Biomarker of Morbidity and Mortality Risk in Sepsis Patients
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2:30 PM – 3:30 PM
ET
(M1430-06-38) Smart Compound Library Based on Machine Learning, Sensing Technology, and Programmable Logic Control
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2:30 PM – 3:30 PM
ET
(M1430-06-39) A Comprehensive Array of Bioanalytical Assays to Assess the Pharmacokinetic Properties of Antibody-Drug Conjugates In Vivo and In Vitro
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2:30 PM – 3:30 PM
ET
(M1430-06-40) Development of an Ultrasensitive qPCR Method to Identify and Quantify Point Mutation in Circulating Tumor DNA
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2:30 PM – 3:30 PM
ET
(M1430-08-49) An In Vitro Model for Acetaminophen Dissolution from Overdosed Oral Formulations
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2:30 PM – 3:30 PM
ET
(M1430-08-50) Leachable Analysis of Ethylene Vinyl Acetate Infusion Bags by GC-FID-MS and LC-UV-MS
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2:30 PM – 3:30 PM
ET
(M1430-08-51) Co-processing PVP with Maltodextrin during Spay-Drying Reduces the Impact of Humid Weather on Product Attributes
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2:30 PM – 3:30 PM
ET
(M1430-08-52) Systematic Root Cause Analysis for Investigation of Contamination Peak in an Ovicidal Topical Product
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2:30 PM – 3:30 PM
ET
(M1430-08-53) Process Analytical Technology for Inline Aerodynamic Particle Size Measurements during Spray Drying
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2:30 PM – 3:30 PM
ET
(M1430-08-54) Analysis of Manufacturing Deficiencies for Immediate Release Tablets in Abbreviated New Drug Applications
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2:30 PM – 3:30 PM
ET
(M1430-08-55) Quantitative Determination of Microcrystalline Cellulose in Drug Products by Chemometrics Analysis of Raman Spectroscopy
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2:30 PM – 3:30 PM
ET
(M1430-09-56) A Model-Based and Quality-by-Design Compatible Lyophilization Cycle Development Strategy for Biopharmaceuticals
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2:30 PM – 3:30 PM
ET
(M1430-09-57) Using Enzymes to Accelerate PS80 Degradation and Elucidate Mechanistic Impacts of PS80 Degradants on Protein Stability via Thermal- and Agitation-Induced Aggregation
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2:30 PM – 3:30 PM
ET
(M1430-09-58) Improvements to PS80 Detection in Drug Product Formulations: A Mixed Mode High-Performance Liquid Chromatography Method for the Quantification and Improvement in the Detection of Polysorbates
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2:30 PM – 3:30 PM
ET
(M1430-09-59) Electrophotographic 3D Printing of Pharmaceutical Films
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2:30 PM – 3:30 PM
ET
(M1430-09-60) Assessing Stress-Induced Amorphization and Excipient Functionality in Tablet Matrices Using Correlative Microscopy Analysis
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2:30 PM – 3:30 PM
ET
(M1430-09-61) Improvement upon a Multi-residue Method for Nitrosamine Analysis in Losartan Drug Product Using an Enhanced LC/MS/MS System
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2:30 PM – 3:30 PM
ET
(M1430-09-62) Strategies for Data Treatment of RTD Curves for Pharmaceutical Applications
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2:30 PM – 3:30 PM
ET
(M1430-10-63) Assessing In Vitro Release Testing (IVRT) in Bioequivalence Studies for Complex Products - Considerations for Ophthalmic versus Topical Dermatological Dosage Forms
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2:30 PM – 3:30 PM
ET
(M1430-10-64) Physiologically Based Biopharmaceutics Modeling of BCS Class I Extended-Release Drug Products: A Preliminary Exploration
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2:30 PM – 3:30 PM
ET
(M1430-10-65) Comparing a t-Distribution Based Bayesian Approach with the Two One-Sided t-Test (TOST) for Bioequivalence Studies in Real-World Datasets
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2:30 PM – 3:30 PM
ET
(M1430-10-66) Assessment of In Vitro and In Vivo Pre-clinical Pharmacokinetics of EPZ015666; a Novel Small Molecule for Medulloblastoma Treatment
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2:30 PM – 3:30 PM
ET
(M1430-10-67) Effect of Food on the Pharmacokinetics of Mitragynine in Rats
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2:30 PM – 3:30 PM
ET
(M1430-10-68) Physiologically-Based Pharmacokinetic (PBPK) Modeling of Oral Absorption of 5-flucytosine to Support Development of a Sustained-Release Formulation for Treatment of Cryptococcal Meningoencephalitis
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2:30 PM – 3:30 PM
ET
(M1430-10-69) Disposition and Metabolism of the Cardiac Myosin Inhibitor Aficamten in Humans
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2:30 PM – 3:30 PM
ET
(M1430-11-70) A Strategy for Optimizing Precompression Pressure Using In-Die Elastic Recovery
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2:30 PM – 3:30 PM
ET
(M1430-11-71) Development and Characterization of RVG9R-Tansferrin Liposomal Nanoparticles Encapsulating Plasmid GFP for Targeted Delivery to the Brain
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2:30 PM – 3:30 PM
ET
(M1430-11-73) Impact of Quantitative Differences in an Inactive Ingredient on the Performance of Topical Products Containing Lidocaine or Diclofenac Sodium
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2:30 PM – 3:30 PM
ET
(M1430-11-74) Mechanism of Stabilization of Amorphous Solid Dispersion above the Overlap Concentration (
c
*): Delay of the First Nucleation Event
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2:30 PM – 3:30 PM
ET
(M1430-11-75) Rizatriptan Nasal Spray with Effective Olfactory Deposition for Improving Migraine Treatment
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2:30 PM – 3:30 PM
ET
(M1430-11-76) Understanding the Impact of Accelerated Release Testing Conditions on Transport Properties and Release Mechanisms of Drug from Long-Acting Ethylene Vinyl Acetate Implants
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2:30 PM – 3:30 PM
ET
(M1430-12-77) A Rational and Data-Driven Approach to Formulation of Therapeutic Peptides
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2:30 PM – 3:30 PM
ET
(M1430-12-78) Investigating the Effect of Plasticizer Type and Concentration on Kollicoat® SR Films Prepared by Film Casting Technique
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2:30 PM – 3:30 PM
ET
(M1430-12-79) Gatifloxacin Nanoemulsions Prepared by Hot Melt Extrusion/Hot-Homogenization for Bacterial Conjunctivitis.
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2:30 PM – 3:30 PM
ET
(M1430-12-80) Encapsulation in Glucan Particles Promotes Solubility and Anti-biofilm Activity of Natural Poly-actives In-vitro
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2:30 PM – 3:30 PM
ET
(M1430-12-81) Formulation, Optimization, and In Vitro Studies of Atorvastatin Calcium Cocrystals
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2:30 PM – 3:30 PM
ET
(M1430-12-82) Aceclofenac-Loaded Nanoparticulate Carriers with Enhanced Solubilization Using Deep Eutectic Solvents for Improved Transdermal Delivery
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2:30 PM – 3:30 PM
ET
(M1430-12-83) Common Deficiencies Using Alternative Bioequivalence Approach for Metered Dose Inhaler in Abbreviated New Drug Applications
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2:30 PM – 3:30 PM
ET
(M1430-05-30) High-Throughput 3D Bioprinting of Corneal Stromal Equivalents
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3:30 PM – 4:30 PM
ET
(M1530-01-01) A Promising Peptide-Based Universal Vaccine against MERS-CoV and SARS-CoV2 Coronaviruses
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3:30 PM – 4:30 PM
ET
(M1530-01-02) Simultaneous XRD-DSC Analysis Identifies Correct Solid Form Dissolution in Polymer
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3:30 PM – 4:30 PM
ET
(M1530-01-03) Drug Nanocrystals Enable Rapid Formulation Transfer from Liquid-Phase Pre-clinical Testing to First-in-Human Solid Dosage Forms
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3:30 PM – 4:30 PM
ET
(M1530-01-04) Heat Shock Protein-Loaded Mitochondria Containing Microvesicles Protect the Blood-Brain Barrier in Ischemic Stroke
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3:30 PM – 4:30 PM
ET
(M1530-01-05) Nanosac: A Soft Nanocarrier for Systemic siRNA Delivery to Solid Tumors
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3:30 PM – 4:30 PM
ET
(M1530-01-06) Combination Therapy of BRD4/PI3K Dual Inhibitor and Novel Tubulin Inhibitor Efficiently Treats Chemo-Resistant Pancreatic Cancer
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3:30 PM – 4:30 PM
ET
(M1530-02-08) A Versatile Room Temperature Stable Lipid Nanoparticle COVID-19 Protein-Based Vaccine
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3:30 PM – 4:30 PM
ET
(M1530-02-09) Design of Citric Acid Coated Superparamagnetic Iron Oxide Nanoparticles for the Treatment of Lung Cancer
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3:30 PM – 4:30 PM
ET
(M1530-02-10) Encapsulation of Cabazitaxel in Polymeric Nanoparticles and Its Biological Effect on Prostate Cancer Cells
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3:30 PM – 4:30 PM
ET
(M1530-02-11) Formulation and Evaluation of Pulsatile Release Melatonin Capsule (Single and Multiple Unit Pellets) for Circadian Rhythm Sleep Disorders
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3:30 PM – 4:30 PM
ET
(M1530-02-12) Multiphysics Modeling and Experimental Design of Novel Ocular Drug Delivery Systems for Glaucoma Treatment
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3:30 PM – 4:30 PM
ET
(M1530-02-13) Preparation of Nanoparticles Based on Krafft Point of Nonionic Polyoxyethylated Amphiphiles
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3:30 PM – 4:30 PM
ET
(M1530-02-14) β-catenin Inhibition Using XAV939 Nanoparticle Promotes Immunogenic Cell Death and Suppresses Tumor Progression
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3:30 PM – 4:30 PM
ET
(M1530-03-15) Monitoring of Lidocaine Transport through Dermis and Subcutis into Muscle Tissue after Application via Topical Delivery Systems
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3:30 PM – 4:30 PM
ET
(M1530-03-16) Robust Rugose Lipid Microparticles for Respiratory Delivery of Biologics
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3:30 PM – 4:30 PM
ET
(M1530-03-17) Improving Aerodynamic Performance with Spray-Dried Corrugated Chitosan Microparticles
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3:30 PM – 4:30 PM
ET
(M1530-03-18) Understanding the Role of Particle Size of Poloxamer P407 on Properties of Tablet Prepared by Direct Compression Process
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3:30 PM – 4:30 PM
ET
(M1530-03-19) Impact of Food on the Release and Bioaccessibility of an Oral BCS Class IV Compound formulated from Different Conventional and Enabling Formulations using the Dynamic Gastrointestinal Model Tiny-TIM
sg
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3:30 PM – 4:30 PM
ET
(M1530-03-20) Digestion Is a Critical Element for Absorption of Cinnarizine from Supersaturated Lipid-Based Type I Formulations
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3:30 PM – 4:30 PM
ET
(M1530-03-21) Predicting the Relative in Vivo performance of Nanoformed and Crystalline Bulk Piroxicam Solid Suspensions from in Vitro Flux Measurements
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3:30 PM – 4:30 PM
ET
(M1530-05-29) The Effect of Cancer-Associated Cachexia on the Pharmacokinetics of Extra-vascularly Administered Monoclonal Antibodies
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3:30 PM – 4:30 PM
ET
(M1530-05-30) Metformin Induced-Oxidative Stress Modulates LNCaP Cellular Redox Status and Suppressed Cell Growth
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3:30 PM – 4:30 PM
ET
(M1530-05-31) Anti-cancer Sonosensitive DOX-Loaded Liposomes to Avoid Systemic Immunosuppression
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3:30 PM – 4:30 PM
ET
(M1530-05-33) Advancing Lung Cancer Therapy: Development and Optimization of Lorlatinib Loaded Inhaled Nanostructure Lipid Carriers (NLC) Using Design of Experiment Approach
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3:30 PM – 4:30 PM
ET
(M1530-09-56) Navigating Thermal Binder Selection for Rational Design of a Twin-Screw Melt Granulation Process
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3:30 PM – 4:30 PM
ET
(M1530-09-57) Combining Machine Learning and Backgrounded Membrane Imaging: A Case Study in Comparing and Classifying Different Types of Biopharmaceutically Relevant Particles
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3:30 PM – 4:30 PM
ET
(M1530-09-58) Critical Manufacturing Parameters and Their Impacts on the Product Attributes of Bupivacaine Multivesicular Liposomal Formulation (Exparel
®
)
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3:30 PM – 4:30 PM
ET
(M1530-09-60) Doxorubicin HCl Release from Liposomal Doxorubicin Formulations – Autonomous Capillary Electrophoretic (CE) In Vitro Release Test (IVRT) Method
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3:30 PM – 4:30 PM
ET
(M1530-09-62) Quantitation of Ethylene Oxide and Nitrosamines in Excipients and Pharmaceutical Products Using SIFT-MS
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3:30 PM – 4:30 PM
ET
(M1530-10-63) Quantum Electrochemical Spectroscopy (QES): A Novel Approach for Enhanced Detection and Evaluation of Drug-Induced Liver Injury (DILI)
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3:30 PM – 4:30 PM
ET
(M1530-10-64) Repeatability and Reproducibility of Simulated Fasted and Fed State Gastrointestinal Conditions and Paracetamol Bioaccessibility in the Dynamic In Vitro Models TIM-1 and Tiny-TIMsg
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3:30 PM – 4:30 PM
ET
(M1530-10-65) Transforming Growth Factor-Beta (TGF-β) as a Potential Therapeutic Target of Methylseleninic Acid and Seleno-l-Methionine in Clear Cell Renal Cell Carcinoma
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3:30 PM – 4:30 PM
ET
(M1530-10-66) Next Level Drug Research in an Ex Vivo Tissue Gut-on-a-Chip Model: Advanced Applications of the Intestinal Explant Barrier Chip (IEBC)
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3:30 PM – 4:30 PM
ET
(M1530-10-67) Preclinical Pharmacokinetic Study and Lung Penetration of Coumarin Extracted of
Zanthoxylum tingoassuiba
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3:30 PM – 4:30 PM
ET
(M1530-10-68) Assessing the In Vitro Performance of Solid Dosage Forms Over-Encapsulated with the ID-Cap System for Improved Compliance
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3:30 PM – 4:30 PM
ET
(M1530-10-69) A Simulation-Based Decision Guide to Evaluate Missing Data in Bioequivalence Studies
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3:30 PM – 4:30 PM
ET
(M1530-11-71) Development of a Novel Repeat-Action Oral Drug Delivery System for Naproxen and Esomeprazole
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3:30 PM – 4:30 PM
ET
(M1530-11-72) Enhanced Dissolution of Amphotericin B through Development of Amorphous Solid Dispersions Containing Polymer and Surfactants
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3:30 PM – 4:30 PM
ET
(M1530-11-73) Impact of Structural Relaxation in Amorphous Solid Dispersions
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3:30 PM – 4:30 PM
ET
(M1530-11-74) Micellar Codelivery of DQ, a Disulfiram Based Prodrug with In Situ Copper Ions Chelation for Cancer Therapy
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3:30 PM – 4:30 PM
ET
(M1530-11-75) Role of Citric Acid in Enhancing Drug Performance: A Double-Edged Sword?
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3:30 PM – 4:30 PM
ET
(M1530-11-76) Understanding the Role of Water on the Molecular Mobility of Polymer Systems with Terahertz Spectroscopy
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3:30 PM – 4:30 PM
ET
(M1530-12-77) Poloxamer 188 in Amorphous Solid Dispersions of Efavirenz and HPMC-AS Improves In Vitro Dissolution of the Drug but Does Not Affect In Vitro Permeation nor In Vivo Absorption
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3:30 PM – 4:30 PM
ET
(M1530-12-78) Hot and Cold Formulation of Biologics for the Optimization of Drying Technologies
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3:30 PM – 4:30 PM
ET
(M1530-12-79) Development of Antibody Conjugated Nanoparticles for Delivery of Nucleic Acid for Stimulation of Perivascular Macrophages
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3:30 PM – 4:30 PM
ET
(M1530-12-80) A New and Sustainable Twin Screw Wet Granulation Method Making Subsequent Drying Obsolete
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3:30 PM – 4:30 PM
ET
(M1530-12-81) Spatial Heterogeneity in Drug Crystallization in Extrudates Prepared by Hot Melt Extrusion
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3:30 PM – 4:30 PM
ET
(M1530-12-83) Effect of LNP Components on mRNA-Mediated Protein Expression of Lipid Nanoparticles in Different Organs
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