Altis Biosystems developed a series of in vitro, stem cell derived intestinal cell models called Repligut® Systems for use in pre-clinical drug discovery. RepliGut® Systems address current limitations of cell lines and animal models for the accurate representation of human intestinal physiology. Our flagship RepliGut® Planar platform supports donor intestinal stem cells isolated from multiple regions of the intestine that are sequentially proliferated and differentiated into the key cell types in the human gastrointestinal epithelium. RepliGut® Models developed from the different intestine regions recreate the cellular lifecycle of the intestinal crypt and can be used for compound screening, disease modeling, toxicity, efficacy, and basic research studies. RepliGut® Systems can also be used to study many aspects of drug disposition including metabolism and drug absorption. We are proud to have industry leading scientists on our team that share a passion for creating a high-throughput, scalable, and translatable products and services to support accelerated drug development. Our enthusiasm for delivering scientific innovation and building strong industry alliances leads us to approach every challenge and opportunity with vigor, knowing that our proactivity is critical to success